2-O-Methyltransferase

2'-O-Methyltransferase (2OM) is a methyltransferase enzyme encoded by the Vaccinia virus DNA, which is expressed in recombinant E. coli. It is responsible for converting the Cap0 cap structure into a Cap1 cap structure. This enzyme utilizes S-Adenosylmethionine (SAM) as the methyl donor and adds a methyl group at the 2'-O position of the first nucleotide adjacent to the cap structure (Cap0) on RNA, resulting in mRNA with a Cap1 structure. This modification further reduces the immunogenicity of mRNA itself and enhances the expression level of encoded proteins after transfection.

Product Spec.:

10U/μL

• BP-E06 说明书

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